1 National Food Institute, Technical University of Denmark2 Division of Toxicology and Risk Assessment, National Food Institute, Technical University of Denmark3 Finnish Institute of Occupational Health4 Bundesinstitut für Risikobewertung5 European Commission - Joint Research Center6 CrisisTox Consult7 National Institute of Public Health and the Environment8 Health Protection Agency9 Swedish Defence Research Agency10 Institut National de l'Environnement Industriel et des Risques11 Finnish Institute of Occupational Health12 National Institute of Public Health and the Environment13 Health Protection Agency14 Swedish Defence Research Agency
A scientifically sound assessment of the risk to human health resulting from acute chemical releases is the cornerstone for chemical incident prevention, preparedness and response. Although the general methodology to identify acute toxicity of chemicals has not substantially changed in the last decades, there is ongoing debate on the current approaches for human health risk assessment in scenarios involving acute chemical releases.A survey was conducted to identify: (1) the most important present and potential future chemical incident scenarios and anticipated changes in chemical incidents or their management; (2) information, tools and guidance used in different countries to assess health risks from acute chemical releases; and (3) needs for new information, tools, guidance and expertise to enable the valid and rapid health risk assessment of acute chemical exposures.According to the results, there is an obvious variability in risk assessment practices within Europe. The multiplicity of acute exposure reference values appears to result in variable practices. There is a need for training especially on the practical application of acute exposure reference values. Although acutely toxic and irritating/corrosive chemicals will remain serious risks also in future the development of plausible scenarios for potential emerging risks is also needed. This includes risks from new mixtures and chemicals (e.g. nanoparticles).
Journal of Hazardous Materials, 2013, Vol 244-245, p. 545-554
Chemical incidents; Health risk assessment; Acute exposure reference values; Survey