Wild, J B2; Stather, P W3; Biancari, F3; Choke, E C3; Earnshaw, J J3; Grant, S W3; Hafez, H3; Holdsworth, R3; Juvonen, T3; Lindholt, Jes S.4; McCollum, C3; Parvin, S3; Sayers, R D3; Bown, M J3
1 Department of Clinical Medicine - Viborg Regional Hospital, Department of Clinical Medicine, Health, Aarhus University2 Department of Cardiovascular Sciences, Vascular Surgery Group, University of Leicester, Leicester, UK. email@example.com unknown4 Department of Clinical Medicine - Viborg Regional Hospital, Department of Clinical Medicine, Health, Aarhus University
OBJECTIVES: Currently most abdominal aortic aneurysm screening programmes discharge patients with aortic diameter of less than 30 mm. However, sub-aneurysmal aortic dilatation (25 mm-29 mm) does not represent a normal aortic diameter. This observational study aimed to determine the outcomes of patients with screening detected sub aneurysmal aortic dilatation. DESIGN AND METHODS: Individual patient data was obtained from 8 screening programmes that had performed long term follow up of patients with sub aneurysmal aortic dilatation. Outcome measures recorded were the progression to true aneurysmal dilatation (aortic diameter 30 mm or greater), progression to size threshold for surgical intervention (55 mm) and aneurysm rupture. RESULTS: Aortic measurements for 1696 men and women (median age 66 years at initial scan) with sub-aneurysmal aortae were obtained, median period of follow up was 4.0 years (range 0.1-19.0 years). Following Kaplan Meier and life table analysis 67.7% of patients with 5 complete years of surveillance reached an aortic diameter of 30 mm or greater however 0.9% had an aortic diameter of 54 mm. A total of 26.2% of patients with 10 complete years of follow up had an AAA of greater that 54 mm. CONCLUSION: Patients with sub-aneurysmal aortic dilatation are likely to progress and develop an AAA, although few will rupture or require surgical intervention.
European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery, 2013, Vol 45, Issue 2, p. 128-34
Aged; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Dilatation, Pathologic; Disease Progression; Europe; Female; Humans; Kaplan-Meier Estimate; Male; Mass Screening; Middle Aged; Predictive Value of Tests; Prognosis; Retrospective Studies; Time Factors; Vascular Surgical Procedures