Larsen, Lars Erik1; Breum, Solvej Østergaard8; Trebbien, Ramona1; Bradstad, K.9; Nielsen, L. P.9; Chriél, Mariann1; Jensen, Trine Hammer1; Hjulsager, Charlotte Kristiane1; Handberg, Kurt1; Jørgensen, Poul Henrik1; Harslund, Jakob le Fèvre1; Rangstrup-Christensen, Lena1; Petersen, B.10; Hammer, Anne Sofie1
1 National Veterinary Institute, Technical University of Denmark2 Section for Virology, National Veterinary Institute, Technical University of Denmark3 Section for Public sector service and commercial diagnostics, National Veterinary Institute, Technical University of Denmark4 Division of Veterinary Diagnostics and Research, National Veterinary Institute, Technical University of Denmark5 Virology, Division of Veterinary Diagnostics and Research, National Veterinary Institute, Technical University of Denmark6 Division of Poultry, Fish and Fur Animals, National Veterinary Institute, Technical University of Denmark7 Section of Fur Animal Diseases and Wildlife, Division of Poultry, Fish and Fur Animals, National Veterinary Institute, Technical University of Denmark8 National Food Institute, Technical University of Denmark9 Statens Serum Institut10 Holstebro Veterinary Clinic
Influenza in mink (Neovison vison) is assumed to be rare, but several outbreaks have been described during recent years in Europe and the North America. In 2009, influenza A of the subtype H3N2 was detected in several Danish mink farms with respiratory symptoms. Full-genome sequencing showed that the virus was a human/swine reassortant, with the H and N gene most related to human H3N2 viruses circulating in 2005. The remaining 6 genes were most closely related to H1N2 influenza viruses circulating in Danish swine. This virus had not previously been described in swine, mink or humans. PCRs assays specifically targeting the new reassortant were developed and used to screen influenza positive samples from humans and swine in Denmark with negative results. Thus, there was no evidence that this virus had spread to humans or was circulating in Danish pigs. In 2010 and 2011, influenza virus was again diagnosed in diseased mink in a few farms. The genetic typing showed that the virus was similar to the pandemic H1N1 virus circulating in humans and swine. The H3N2 virus was not detected in 2010 and 2011. Taken together, these findings indicate that mink is highly susceptible for influenza A virus of human and swine origin and may therefore act as a potential host/reservoir for influenza A viruses.
Proceedings of the Xth International Scientific Congress in Fur Animal Production: Scientifur Volume 36 (3/4), 2012, p. 153-156
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10th International Scientific Congress in fur animal production (IFASA 2012)