A 12-Year Follow-up Study of Clinical Screening and Predictive Genetic Testing
The penetrance of hypertrophic cardiomyopathy (HCM) during childhood and adolescence has been only sparsely described. We studied the penetrance of HCM and the short- and long-term outcomes of clinical screening and predictive genetic testing of child relatives of patients with HCM.
Circulation, 2013, Vol 127, Issue 1, p. 48-54
Journal Article; Adolescent; Adult; Age of Onset; Cardiomyopathy, Hypertrophic, Familial; Child; Echocardiography; Electrocardiography; Family; Follow-Up Studies; Genetic Predisposition to Disease; Genetic Testing; Heterozygote; Humans; Penetrance; Phenotype; Predictive Value of Tests; Risk Factors; Sarcomeres