Antiresorptive treatment reduces the risk of fractures, but most patients remain at elevated risk. We used health registers to identify predictors of new major osteoporotic fractures in patients adhering to alendronate. Risk factors showed a different pattern than in the general population and included dementia, ulcer disease, and Parkinson's disease.
Osteoporosis International, 2013, Vol 24, Issue 1, p. 321-8
Adult Age Factors Aged Aged, 80 and over Alendronate/*therapeutic use Bone Density Conservation Agents/*therapeutic use Comorbidity Dementia/epidemiology Denmark/epidemiology Female Humans Male Medication Adherence Middle Aged Osteoporosis/drug therapy Osteoporotic Fractures/*epidemiology/*prevention & control Polypharmacy Registries Risk Factors Sex Factors Treatment Failure Ulcer/epidemiology; Journal Article