Elevated plasma N-terminal (NT)-proBNP from the heart as well as white matter hyperintensities (WMH) in the brain predict cardiovascular (CV) mortality in the general population. The cause of poor prognosis associated with elevated P-NT-proBNP is not known but WMH precede strokes in high risk populations. We assessed the association between P-NT-proBNP and WMH or brain atrophy measured with magnetic resonance imaging (MRI) in type 2 diabetic patients, and age-matched controls.
Cardiovascular Diabetology, 2012, Vol 11, Issue 119, p. 119-127
3-D Magnetic Ressonance Imaging; Brain Parenchymal Fraction; Plasma NT-proBNP; Type 2 Diabetes; White Matter Hyperintensities; Journal Article