Pretreatment of skin with ablative fractional lasers (AFXL) enhances the uptake of topical photosensitizers used in photodynamic therapy (PDT). Distribution of photosensitizer into skin layers may depend on depth of laser channels and incubation time. This study evaluates whether depth of intradermal laser channels and incubation time may affect AFXL-assisted delivery of methyl aminolevulinate (MAL).
Lasers in Surgery and Medicine, 2012, Vol 44, Issue 10, p. 787-95
Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't