1 Department of Photonics Engineering, Technical University of Denmark2 Teraherts Technologies and Biophotonics, Department of Photonics Engineering, Technical University of Denmark3 Office for Law and Contracts, Administration, Technical University of Denmark
The cell-BOCS is a novel microfluidics based cell-sorting instrument utilizing next generation optical trapping technology developed at the Technical University of Denmark. It is targeted emerging bio-medical research and diagnostics markets where it for certain applications offers a number of advantages over conventional fluorescence activated cell-sorting (FACS™) technology. Advantages include gentle handling of cells, sterile sorting, easy operation, small footprint and lower cost allowing out-of-core-facility use. Application examples are found within sorting of fragile transfected cells, high value samples and primary cell lines, where traditional FACS technology has limited application due to it’s droplet-based approach to cell-sorting. In the diagnostics field, in particular applying the cell-BOCS for isolating pure populations of circulating tumor cells is an area that has generated a lot of interest.
Proceedings of Spie, the International Society for Optical Engineering, 2012, Vol 8274