Schwartz, Gregory G2; Olsson, Anders G2; Abt, Markus2; Ballantyne, Christie M2; Barter, Philip J2; Brumm, Jochen2; Chaitman, Bernard R2; Holme, Ingar M2; Kallend, David2; Leiter, Lawrence A2; Leitersdorf, Eran2; McMurray, John J V2; Mundl, Hardi2; Nicholls, Stephen J2; Shah, Prediman K2; Tardif, Jean-Claude2; Wright, R Scott2
1 Department of Clinical Medicine - The Department of Cardiological Medicine B, Department of Clinical Medicine, Health, Aarhus University2 unknown
In observational analyses, higher levels of high-density lipoprotein (HDL) cholesterol have been associated with a lower risk of coronary heart disease events. However, whether raising HDL cholesterol levels therapeutically reduces cardiovascular risk remains uncertain. Inhibition of cholesteryl ester transfer protein (CETP) raises HDL cholesterol levels and might therefore improve cardiovascular outcomes.
Briefings From the New England Journal of Medicine (spanish Edition), 2012, Vol 367, Issue 22, p. 2089-99