Occupational allergic contact eczema and asthma caused by bleaching agents is seen in hairdressers. Bleaching agents contain persulfate salts, which are known to induce immediate reactions such as rhinitis, asthma, contact urticaria, and anaphylaxis. The immunologic mechanism is not, however, fully understood. The specific inhalation challenge test is considered to be the gold standard for diagnosing occupational asthma and rhinitis. However, this test is not always accessible. Therefore, the diagnosis of occupational allergic asthma caused by persulfate salts is made by combining a clinical history, a diagnosis of asthma, and a positive skin prick test (SPT). Standardized methods for performing SPT with persulfate salts are warranted. A case of a young hairdresser with occupational asthma and hand eczema caused by persulfate salts is presented, and the procedure for performing the SPT with ammonium persulfate and potassium persulfate is described in detail.
Dermatitis, 2012, Vol 23, Issue 6, p. 284-7
Asthma; Dermatitis, Allergic Contact; Dermatitis, Occupational; Facial Dermatoses; Female; Hair Dyes; Hair Preparations; Hand Dermatoses; Humans; Occupational Exposure; Risk Factors; Young Adult; Case Reports; Journal Article; Research Support, Non-U.S. Gov't