1 Clinical Pathology, Institute of Regional Health Research, Det Sundhedsvidenskabelige Fakultet, SDU2 Center Lillebaelt, Institute of Regional Health Research, Det Sundhedsvidenskabelige Fakultet, SDU3 unknown4 Clinical Pathology, Institute of Regional Health Research, Det Sundhedsvidenskabelige Fakultet, SDU
The effect of triaging women with atypical squamous cells of undetermined significance (ASC-US) with human papillomavirus (HPV) DNA testing has been well documented. New tests detecting HPV E6/E7 mRNA are emerging, claiming to be more specific for detecting high-grade disease. We evaluated the clinical performance of two HPV tests: the Linear Array HPV genotyping test (LA) detecting HPV DNA from 37 oncogenic and non-oncogenic HPV types and the Aptima HPV assay detecting E6/E7 mRNA from 14 oncogenic HPV types.
Cytopathology, 2012, Vol 23, Issue 6, p. 389-395
Adult; Aged; Carcinoma, Squamous Cell; Cervical Intraepithelial Neoplasia; Confidence Intervals; DNA, Viral; Female; Follow-Up Studies; Human Papillomavirus DNA Tests; Humans; Middle Aged; Papillomaviridae; Papillomavirus Infections; RNA, Messenger; RNA, Viral; Sensitivity and Specificity; Triage; Uterine Cervical Neoplasms; Young Adult