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Teduglutide reduces need for parenteral support among patients with short bowel syndrome with intestinal failure

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Authors:
  • Jeppesen, Palle B ;
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    Gastroenterology, Department of, Abdominal Centre, Rigshospitalet, The Capital Region of Denmark
  • Pertkiewicz, Marek ;
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    unknown
  • Messing, Bernard ;
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    unknown
  • Iyer, Kishore ;
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    unknown
  • Seidner, Douglas L ;
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    unknown
  • O'keefe, Stephen J D ;
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    unknown
  • Forbes, Alastair ;
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    unknown
  • Heinze, Hartmut ;
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    unknown
  • Joelsson, Bo
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    unknown
DOI:
10.1053/j.gastro.2012.09.007
Abstract:
Teduglutide, a glucagon-like peptide 2 analogue, might restore intestinal structural and functional integrity by promoting growth of the mucosa and reducing gastric emptying and secretion. These factors could increase fluid and nutrient absorption in patients with short bowel syndrome with intestinal failure (SBS-IF). We performed a prospective study to determine whether teduglutide reduces parenteral support in patients with SBS-IF.
Type:
Journal article
Language:
English
Published in:
Gastroenterology, 2012, Vol 143, Issue 6
Keywords:
Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Main Research Area:
Medical science
Publication Status:
Published
Review type:
Peer Review
Submission year:
2012
Scientific Level:
Scientific
ID:
232899797

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