the influence of preexisting comorbidity and genetic confounding: a danish nationwide register-based cohort study of twins and singletons
Hyperthyroidism is associated with severe comorbidity, such as stroke, and seems to confer increased mortality. However, it is unknown whether this increased mortality is explained by hyperthyroidism per se, comorbidity, and/or genetic confounding.
Journal of Clinical Endocrinology and Metabolism, 2012, Vol 97, Issue 11, p. 4123-9
Adolescent; Adult; Aged; Aged, 80 and over; Cohort Studies; Comorbidity; Denmark; Diseases in Twins; Female; Genetic Predisposition to Disease; Humans; Hyperthyroidism; Incidence; Male; Middle Aged; Prevalence; Registries; Twins