{"controller"=>"catalog", "action"=>"show", "id"=>"232103679"}
  • EN
  • DA

Danish NationalResearch Database

  • Search Publications & Researchers
  • Open Access Indicator
  • Publications
  • Researchers
Example Finds records
water{} containing the word "water".
water supplies"{}" containing the phrase "water supplies".
author:"Doe, John"author:"{}" containing the prase "Doe, John" in the author field.
title:IEEEtitle:{} containing the word "IEEE" in the title field.
Need more help? Advanced search tutorial
  • Selected (0)
  • History

Parvovirus B19 Infection in the First Trimester of Pregnancy and Risk of Fetal Loss

    • Save to Mendeley
    • Export to BibTeX
    • Export to RIS
    • Email citation
Authors:
  • Lassen, Jonathan ;
    Close
    unknown
  • Jensen, Anne K V ;
    Close
    unknown
  • Bager, Peter ;
    Close
    unknown
  • Pedersen, Carsten B ;
    Close
    Orcid logo0000-0003-2077-8533
    Department of Economics and Business Economics - National Centre for Register-based Research, Department of Economics and Business Economics, Aarhus BSS, Aarhus University
  • Panum, Inge ;
    Close
    Department of Biomedicine - Medical Microbiology and Immunology, Department of Biomedicine, Health, Aarhus University
  • Nørgaard-Pedersen, Bent ;
    Close
    unknown
  • Aaby, Peter ;
    Close
    SUND ph.d. skole
  • Wohlfahrt, Jan ;
    Close
    School of Public Health, Faculty of Health Sciences, Aarhus University, Aarhus University
  • Melbye, Mads
    Close
    unknown
Subtitle:
A Population-based Case-Control Study
DOI:
10.1093/aje/kws177
Abstract:
Because parvovirus B19 infection during pregnancy has been associated with increased risk of fetal loss in small or selected study populations, the authors evaluated the risk in a population-based study. A nested case-control study was conducted by using a population-based screening for syphilis in 3 regions in Denmark from 1992 to 1994. Cases of women with fetal loss were identified in the National Patient Register (n = 2,918), and control women with live-born children were identified in the Medical Birth Register (n = 8,429) by matching on age and sampling week. First-trimester serum samples were tested for parvovirus B19 immunoglobulin M positivity. Parvovirus B19 immunoglobulin M positivity was associated with a 71% increased risk of fetal loss (odds ratio = 1.71, 95% confidence interval: 1.02, 2.86). Adjustment for number of children or stratifying for gestational age at loss did not change the risk estimate. Assuming causality, only 0.1% of fetal losses were attributable to parvovirus B19 positivity, a proportion which could increase to approximately 1% during epidemic periods. In conclusion, acute parvovirus B19 infection during the first trimester of pregnancy was associated with an increased risk of fetal loss. However, the impact on the overall burden of fetal losses appeared small even during epidemics.
Type:
Journal article
Language:
English
Published in:
American Journal of Epidemiology, 2012, Vol 176, Issue 9, p. 803-7
Keywords:
Case-Control Studies; Denmark; Female; Fetal Death; Gestational Age; Humans; Immunoglobulin M; Parvoviridae Infections; Parvovirus B19, Human; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, First; Risk Factors; Journal Article; Research Support, Non-U.S. Gov't
Main Research Area:
Social science
Publication Status:
Published
Review type:
Peer Review
Submission year:
2012
Scientific Level:
Scientific
ID:
232103679

Full text access

  • Doi Get publisher edition via DOI resolver
Checking for on-site access...

On-site access

At institutions

  • Capital region
  • Aarhus university.en

Metrics

Feedback

Sitemap

  • Search
    • Statistics
    • Tutorial
    • Data
    • FAQ
    • Contact
  • Open Access
    • Overview
    • Development
    • FAQ
    • Contact
  • About
    • Institutions
    • Release History
    • Cookies and privacy policy

Copyright © 1998–2018.

Fivu en