Ballou, Byron3; Ernst, Lauren A.3; Andreko, Susan3; Fitzpatrick, James A. J.3; Lagerholm, B. Christoffer4; Bruchez, Marcel3; Waggoner, Alan S.3
1 Department of Physics, Chemistry and Pharmacy, Faculty of Science, SDU2 Faculty of Science, SDU3 Carnegie Mellon University4 Department of Physics, Chemistry and Pharmacy, Faculty of Science, SDU
Quantum dots are ideal probes for fluorescent imaging of vascular and lymphatic tissues. On injection into appropriate sites, red- and near-infrared-emitting quantum dots provide excellent definition of vasculature, lymphoid organs, and lymph nodes draining both normal tissues and tumors. We detail methods for use with commercially available quantum dots and discuss common difficulties.
Methods in Molecular Biology, 2009, Vol 574, p. 63-74