Nguyen, Tri Hieu3; Hansen, Poul Erik2; Duus, Fritz4; Heilmann, Gørg5; Pham, Dinh Hung3; Nguyen, Lien Hoa Dieu3
1 The Department of Science, Systems and Models, Roskilde University2 Funktionelle Biomaterialer, Department of Science and Environment, Roskilde University3 University of Science of Ho Chi Minh City4 Department of Science and Environment, Roskilde University5 University of Regensburg
Three chromanone acids, blancoic acid (1), isoblancoic acid (2) and chapelieric acid (3), were isolated from the bark of Calophyllum dongnaiense Pierre collected in Dong Nai Province. Their structures were elucidated using spectroscopic techniques (1-D and 2-D NMR, UV, IR and MS) as well as chemical methods. Cytotoxicity of compounds 1-3 and their 5-O-acetylated and methylated derivatives against Hela cell line was examined.