1 The Department of Science, Systems and Models, Roskilde University2 Molekylær og generel fysiologi, Department of Science and Environment, Roskilde University3 Princeton University
Growth environments are important metabolic and developmental regulators. Here we demonstrate a growth environment-dependent effect on Caulobacter chromosome segregation of a small-molecule inhibitor of the MreB bacterial actin cytoskeleton. Our results also implicate ParAB as important segregation determinants, suggesting that multiple distinct mechanisms can mediate Caulobacter chromosome segregation and that their relative contributions can be environmentally regulated.
Journal of Bacteriology, 2009, Vol 191, Issue 3, p. 1097-1100