Shiguetomi Medina, Juan Manuel3; Rahbek, Ole3; Stødkilde-Jørgensen, Hans4; Møller-Madsen, Bjarne3
1 Department of Clinical Medicine - The Department of Orthopaedics E, ?AS, Department of Clinical Medicine, Health, Aarhus University2 Department of Clinical Medicine - The MR Research Centre, Department of Clinical Medicine, Health, Aarhus University3 Department of Clinical Medicine - The Department of Orthopaedics E, ?AS, Department of Clinical Medicine, Health, Aarhus University4 Department of Clinical Medicine - The MR Research Centre, Department of Clinical Medicine, Health, Aarhus University
Objective Development of a new technique for epiphysiodesis using radiofrequency ablation on an animal model (pig) that involves less scarring, less exposure to X-rays, and reduces the risk of injuring the surrounding structures compared to current methods. Material and Methods 4 non-mature 40 kg pigs were used. A control leg was randomly selected and the contralateral treated at two ablation sites (lateral and medial) identified at the proximal tibia growth plate using x-ray. Under general anesthesia, a probe was inserted and the ablation performed. T1, T2 and water content MR images were performed right after the procedure and 12 weeks later.The length of both tibiae was measured immediately after the ablation and at the end of the study. Results Both legs were equal at the beginning of the study and there was a leg length difference in average of 3.7mm (SD=0.48) at the end. No damage to the surrounding cartilage structures was found. The animals could walk normally after the anesthesia and no signs of pain or discomfort were presented during the follow-up period. Conclusions Epiphysiodesis using radio frequency ablation is an innovative technique that may represent an alternative way of treatment. These results show that this technique can arrest growth in a safe effective way. However, longer studies must be performed to obtain more evidence of both the safety and effectiveness of the procedure.