In 2001 we commemorate the 4th centenary of the death of Tycho Brahe, perhaps the first great scientists in a modern sense.This famous Danish astronomer died in Prague on the 24th of October 1601, eleven days after he had attended a banquet at the Bohemian count of Rosenberg. Tycho was too courteous to obey the calls of nature during the hour-long dinner and finally his bladder burst, which led to his death. Or so the story goes. But is this the real cause of Tycho's death? Is it at all possible to die from a burst bladder? Or are there more likely explanations of his death?