Although non-linear reconstruction has shown potential for shortening acquisition times, its clinical usage is often hampered by the lengthy reconstruction time. To speedup non-linear reconstruction and enable its clinical usage, we have extended previously published Gadgetron framework to support cloud computing. With this extension (named GT-Plus), any number of Gadgetron processes can run cooperatively across multiple computers. GT-Plus framework was deployed on Amazon EC2 cloud and NIH’s Biowulf system. We demonstrate that with the GT-Plus cloud, a multi-slice free-breathing myocardial cine imaging with the whole ventricular coverage can be completed within 1min, including data acquisition and reconstruction.