1 Nuklearmedicinsk Afdeling, Aalborg Sygehus, Faculty of Health Sciences, Aarhus University, Aarhus University2 Sheffield University Hospital, Dept of Radiology, Sheffield, United Kingdom3 unknown4 Department of Clinical Medicine, Health, Aarhus University5 Department of Clinical Medicine, Health, Aarhus University
PURPOSE F18 FDG PET CT is an established molecular imaging technique most commonly used in the diagnosis and staging of oncological conditions. A rapidly growing clinical application of PET CT is in the investigation of inflammatory and infectious diseases. A review of PET CT scans performed in a tertiary referal centre is presented illustrating its applications and clinical value in the evaluation of suspected or known inflammatory conditions. METHOD AND MATERIALS a retrospective case review of 59 patients was carried out. all patients underwent PET CT scanning after multiple diagnostic investigations failed to determine a diagnosis. RESULTS PET CT was useful in all 59 cases; revealing malignancy in 11 (2 of whom had associated myositis), systemic vasculitis in 9, inflammatory arthropathy in 5, infectious/other inflammatory process in 8 and helped to exclude malignant or inflammatory process in 26 patients. CONCLUSION F18 FDG PET CT has the potential to develop into a valuable tool in the diagnostic work up of a variety of infectious, inflammatory and paraneoplastic type conditions. there is a growing body of evidence to support its earlier use in the investigation of patients presenting with these conditions, enabling earlier diagnosis and treatment. CLINICAL RELEVANCE/APPLICATION FDG PET CT should be considered early in the diagnostic work up of patients with inflammatory type, often vague, symptoms and signs.