The food-related lifestyle instrument (FRL) is a 69-item survey questionnaire measuring 23 lifestyle dimensions in five life domains: (a) ways of shopping, (b) cooking methods, (c) quality aspects, (d) consumption situations, and (e) purchasing motives. In the first part of the analysis, consumer samples from Denmark (N = 1209), France (N = 1000), Germany (N = 1000), Spain (N = 1000) and the U.K. (N = 1000) are tested for cross-cultural validity using multi-sample confirmatory factor analysis with structured means. Results indicate that the factorial structure is invariant, between countries in terms of factor pattern, factor loadings, factor covariances and factor variances. In the second factor part of the analysis, replication samples from France (N1 = 1000, N2 = 1000), Germany (N1 = 1000, N2 = 1042), and the UK (N1 = 1000, N2 = 1000) are examined for intra-cultural stability using the same statistical models. Results indicate that the factorial structure is completely invariant over time (in terms of factor pattern, factor loadings, factor covariances, factor variances, item bias, and item reliabilities) in three of five FRL domains, and only subject to minor variations in the other two domains.