Lange, Aksel5; Funch-Jensen, Peter6; Schiøtz, Peter Oluf5
1 The Department of Paediatrics, Faculty of Health Sciences, Aarhus University, Aarhus University2 The Department of Surgical Gastroenterology L, Faculty of Health Sciences, Aarhus University, Aarhus University3 Department of Clinical Medicine - Department of Paediatrics, Department of Clinical Medicine, Health, Aarhus University4 Department of Clinical Medicine, Health, Aarhus University5 Department of Clinical Medicine - Department of Paediatrics, Department of Clinical Medicine, Health, Aarhus University6 Department of Clinical Medicine, Health, Aarhus University
Background: Gastrointestinal symptoms have been reported in association with myoelectrical dysrhythmia, where different types of gastric electrical activity have been described. These types of gastric myoelectrical activity and dysrhythmia can be measured by electrogastrography using cutaneous electrodes. Epigastric impedance is a non-invasive method used to study gastric emptying time and gastric phasic activity.At present no studies of gastric dysrhythmia, measured with epigastric impedance, have been presented, and the purpose of the present study was to investigate gastric rhytms by means of impedance gastrography in control infants compared to infants with different gastrointestinal diseases, before and after treatment of their disease.Method: 21 patients (0-2 months) and 40 healthy infants (0-2 months) were investigated. The patients suffered from partial or total intestinal obstruction, necrotising enterocolitis or pyloric stenosis. All infants were fasting and were studied during periods of at least one hour. The patients were examined in the acute state and after treatment when possible.Results: A pathological result was found in 90 % of the patients. A persistent phasic activity pattern was found in 19 of the 21 patients, high frequency phasic activity in 11 of the 21 patients. Short-term phasic activity was only found in 13 of 40 of the normal infants (32.5%).Conclusion: Using epigastric impedance we found that infants with partial or total intestinal obstruction had gastric phasic activity, which were not found in control infants. The origin of the gastric phasic activity patterns is unknown, but they may be related to electrical control activity.