In this talk, we will describe general pathways involved in the photophysics of a photosensitized process, which can lead to crosslinking due to light excitation of Riboflavin in the cornea. Furthermore, we will show the contribution of singlet molecular oxygen O2(a1Δg) to this phenomena and show difficulties of the measurement in porcine corneas in respect to neat solutions. We will also discuss the mechanism which involves the formation of singlet oxygen as one of the triggering species.
cornea biomechanics; Riboflavin; Singlet Oxygen; quencher; crosslinking
Main Research Area:
7th International Congress of Corneal Cross-Linking, 2011