Larsen, Thomas Ostenfeld3; Perry, N.B.4; Andersen, Birgitte5
1 Center for Microbial Biotechnology, Department of Systems Biology, Technical University of Denmark2 Department of Systems Biology, Technical University of Denmark3 Natural Product Discovery, Department of Biotechnology and Biomedicine, Technical University of Denmark4 unknown5 Fungal Degradation, Department of Biotechnology and Biomedicine, Technical University of Denmark
A new metabolite, infectopyrone (1), has been isolated from the filamentous fungus Alternaria infectoria. The structure of 1 was elucidated by analysis of 2D NMR spectroscopic data. Compound 1 is an alpha-pyrone resembling known toxins, and is a useful phenotaxonomic marker for the A. infectoria species-group. Infectopyrone (1) was also produced by species within Stemphyllium and Ulocladium, and found in mouldy food.
Tetrahedron Letters, 2003, Vol 44, Issue 24, p. 4511-4513