1 Department of Micro- and Nanotechnology, Technical University of Denmark2 Microfluidics Theory and Simulation, Department of Micro- and Nanotechnology, Technical University of Denmark3 Magnetic Systems, Department of Micro- and Nanotechnology, Technical University of Denmark4 Department of Physics, Technical University of Denmark
A new hybrid magnetic bead separator that combines an external magnetic field with 175@mm thick current lines buried in the back side of a silicon wafer is presented. A microfluidic channel was etched into the front side of the wafer. The large cross-section of the current lines makes it possible to use larger currents and obtain forces of longer range than from thin current lines at a given power limit. Guiding of magnetic beads in the hybrid magnetic separator and the construction of a programmable microarray of magnetic beads in the microfluidic channel by hydrodynamic focusing is presented.
Journal of Magnetism and Magnetic Materials, 2007, Vol 311, Issue 1, p. 409-415