The objective of Task 7.5 was to develop tools for model-based planning of sampling campaigns in the design of monitoring strategies for priority pollutant emission barriers. Using integrated urban wastewater system (IUWS) models, measurement campaigns can be designed to improve the calibration of the model‟s parameters (Optimal Experiment Design for Parameter Estimation (OED/PE)). Furthermore, the knowledge contained in the IUWS models can be used to optimize the planning of sampling campaigns aiming at assessing the efficiency of emission control strategies. To do this, the emission barriers need to be implemented in the IUWS model, as well as the sampling and measuring devices that will be used. The simulation results are presented as a Substance Flow Analysis (SFA). These SFAs can be compared with empirical SFAs and can also be used to set up measurement campaigns aiming at gathering information to establish or improve empirical SFAs (OED/SFA). Moreover, the national Danish environmental monitoring programs were compared to the US programs under the Clean Water Act and the proposed environmental monitoring of the European water courses as described in the European Water Framework Directive. Also, kinetic passive sampling methods for the measurement of average water concentrations are presented.