Durbin, Richard2; Eddy, Sean3; Krogh, Anders Stærmose4; Mitchison, Graeme5
1 Department of Biotechnology, Technical University of Denmark2 Sanger Centre - Informatics Division3 Washington University in St. Louis4 Department of Chemistry, Technical University of Denmark5 Medical Research Council
Probabilistic models of proteins and nucleic acids
This book provides an up-to-date and tutorial-level overview of sequence analysis methods, with particular emphasis on probabilistic modelling. Discussed methods include pairwise alignment, hidden Markov models, multiple alignment, profile searches, RNA secondary structure analysis, and phylogenetic inference.