In the micro scale, gripping devices are working in the different way. New forces, working in the micro scale, like van der Waals, surface tension and electrostatics are influencing the gripping process. Handling of micro or even nano sized objects can be easily in the nature. Different types of handling can be found in for example insect everyday life, cells, enzymes etc. To find out these principles we need special tools, like BioDlab database, which is created specially to find the examples form the biology in order to solve engineering problems. In this report different principles of handling at the micro and nano level are presented as well as solutions for micro assembly principles are introduced, concentrating on the adhesion and releasing during the picking and releasing stages of the handling scenario.